The Association Between Intestinal Flora and Lung Cancer and the Regulatory Role of Dietary Fiber

Huizi Wu

doi:10.54097/p06r5454

Authors

Huizi Wu

DOI:

https://doi.org/10.54097/p06r5454

Keywords:

Lung Cancer; Intestinal Flora; Dietary Fiber; SCFA; Prebiotics.

Abstract

Lung cancer accounts for a large proportion of malignant tumor-related deaths. In recent years many studies have demonstrated that dysbiosis is associated with carcinoma of the lungs. Intestinal flora is one of the most complex and diverse microbial populations in the human body. The intestinal flora can maintain a dynamic balance under normal circumstances and has the functions of promoting metabolism and enhancing immunity. This mechanism is partly dependent on short-chain fatty acids (SCFA) produced by the gut microbiota. Dietary fiber provides nutrition for intestinal flora, regulates the diversity and richness of intestinal flora. It also occupies a dominate position in the prevention and treatment of certain diseases. When lung cancer-related microbiota is modulated by dietary fiber, they may have an influence on the lung cancer development. In this paper, the mechanism of intestinal flora and dietary fiber affecting the role of intestinal flora and dietary fiber in lung cancer, respectively, and the correlation between them were summarized.

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