Progress of Therapy in Epilepsy

Abstract

Nowadays, over 50 million people worldwide suffer from epilepsy, with its origins often linked to brain injuries or genetic factors. Despite advancements in medical research, the cause of epilepsy remains elusive for approximately 70% of patients, highlighting a significant gap in our understanding of the disorder. Moreover, because of problems including medication resistance and side effects from conventional Antiseizure medications (ASMs), new approaches to therapy are needed. This review summarizes different mechanisms and Available therapies for epilepsy, and point out some new and developing treatments with an emphasis on precision medicine and innovative pharmacological targets. GPCRs and neuroinflammatory pathways have the potential to be effective therapeutic targets, according to some novel literature review. By customizing medicines to each patient's unique genetic profile, these developments, when combined with precision medicine, are increasing treatment efficacy and decreasing adverse effects. This research suggests that if this emerging discovery incorporated into clinical practice in the future, it may improve patient quality of life and worldwide epilepsy care and public health policies should be strengthened.