The Research Progress on the Improvement and Safety of Steviol Glycosides in Dyslipidemia of Diabetic Rats

Authors

  • Yixuan Li

DOI:

https://doi.org/10.54097/qwhpty29

Keywords:

Steviol glycosides; Diabetes; Dyslipidemia; Insulin; Safety.

Abstract

Steviol glycosides, as natural sweeteners, are highly favored in the market. Moreover, they have shown outstanding effects in improving dyslipidemia. Most diabetic patients experience dyslipidemia, significantly increasing their risk of cardiovascular diseases. Steviol glycosides can improve dyslipidemia in rats by enhancing lipid metabolism, improving insulin conditions, and exhibiting antioxidant and anti-inflammatory properties. There have been no reports of toxicity or allergic reactions from the use of steviol glycosides in the past, and extensive research currently confirms their safety. Therefore, steviol glycosides hold promise as an adjunct medicinal food for improving dyslipidemia in diabetic patients, promoting their application in the medical and food industries.

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References

[1] Tan J, Liao N, Zhang B. Development, application, and prospects of natural sweeteners[J]. China Food Additives, 2022, 33(1).

[2] Kurek J M, Król E, Krejpcio Z. Steviol glycosides supplementation affects lipid metabolism in high-fat fed STZ-induced diabetic rats[J]. Nutrients, 2020, 13(1): 112.

[3] Kurek J M, Mikołajczyk-Stecyna J, Krejpcio Z. Steviol glycosides from Stevia rebaudiana Bertoni mitigate lipid metabolism abnormalities in diabetes by modulating selected gene expression–An in vivo study[J]. Biomedicine & Pharmacotherapy, 2023, 166: 115424.

[4] Gu W, Rebsdorf A, Anker C, et al. Steviol glucuronide, a metabolite of steviol glycosides, potently stimulates insulin secretion from isolated mouse islets: Studies in vitro[J]. Endocrinology, Diabetes & Metabolism, 2019, 2(4): e00093.

[5] Orellana-Paucar A M. Steviol glycosides from Stevia rebaudiana: An updated overview of their sweetening activity, pharmacological properties, and safety aspects[J]. Molecules, 2023, 28(3): 1258.

[6] Jahangir Chughtai M F, Pasha I, Zahoor T, et al. Nutritional and therapeutic perspectives of Stevia rebaudiana as emerging sweetener; a way forward for sweetener industry[J]. CYTA-Journal of Food, 2020, 18(1): 164-177.

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Published

29-11-2024

Issue

Section

Articles

How to Cite

Li, Y. (2024). The Research Progress on the Improvement and Safety of Steviol Glycosides in Dyslipidemia of Diabetic Rats. Academic Journal of Science and Technology, 13(2), 254-256. https://doi.org/10.54097/qwhpty29