Epidemiological Investigation of Chronic Cough in Chongqing


  • Jian He
  • Zhijiao Jiang
  • Feng Xu
  • Xuemei Zhang
  • Changchun Yin
  • Yongxiu Yao
  • Jing Huang




Chongqing Area, Chronic Cough, Covid-19 Infection, Epidemiology


Objective to investigate the incidence and risk factors of chronic cough in Chongqing urban residents aged 18-80 years. Methods a questionnaire was designed, and the incidence and related data of chronic cough among residents aged 18-80 years in Chongqing urban area were statistically analyzed in the form of community field questionnaire. Results a total of 1851 questionnaires were used, of which 1804 were valid. The total incidence of chronic cough was 11.64%, Before the prevalence of covid-19, it was 10.65%, The prevalence of covid-19 was 12.14%. Multivariate analysis of chronic cough showed that the patients were 50 years old or older (or=2.063, 95% CI 1.476-2.883, P<0.05), P<0.05), Senior high school and below (or=0.601, 95% CI 0.430-0.840, P<0.05), 497, 95% CI 1. 784-3. 494, P<0.05), Smoking (or=2.055, 95% CI 1.465-2.882, P<0.05), P<0.05), Drinking (or=2.415, 95% CI 1.692-3.446, P<0.05), P<0.05), Infection with covid-19 (or=1.902, 95% CI 1.387-2.608, P<0.05), P<0.05) the incidence of chronic cough in residents was significantly increased. Multivariate analysis of the severity of chronic cough showed that the risk of severe chronic cough in patients aged 50 years and over was 3.584 times higher than that in patients aged less than 50 years (or=3.584, 95% CI 1.304-9.846, P<0.05), P<0.05), Secondly, the influence of season on cough severity was also statistically significant (or=3.689, 95% CI 1.233-11.038, P<0.05), P<0.05). Multiple correspondence analysis (MCA) of chronic cough related factors showed that the severity of cough was moderately correlated with the impact on life and mood. Conclusion the incidence of chronic cough during the epidemic period of new coronavirus is increased. The incidence of chronic cough is higher in residents aged 50 and above, with lower education (high school and below), smoking and drinking, complicated with chronic respiratory diseases, and infected with covid-19. Chronic cough in patients aged 50 years and above is more serious, and chronic cough significantly affects the daily life and mood of residents. It is necessary to pay attention to the chronic cough group and get timely and effective diagnosis and treatment.


Download data is not yet available.


Asthma group, respiratory branch, Chinese Medical Association Guidelines for the diagnosis and treatment of cough (2021). Chinese Journal of tuberculosis and respiration 2022; 45 (1): 13-46 doi: 10.3760/cma.j.cn112147-20211101-00759.

National respiratory medicine center, respiratory disease branch, Chinese Medical Association Expert consensus on diagnosis and treatment of covid-19 cough Chinese Journal of tuberculosis and respiration 2023; 46 (3): 217-27 doi: 10. 3760/ cma. j.cn112147-20230109-00010.

Braido F, Baiardini I, Tarantini F, et al. Chronic cough and QOL in allergic and respiratory diseases measured by a new specific validated tool cciq. J investig allergy Clin immunol. 2006; 16 (2): 110-6 Epub 2006/05/13. PubMed PMID: 1668 9184.

Chung KF. Measurement of cough. respir Physiol neurobiol. 2006; 152 (3): 329-39 Epub 2006/03/15. doi: 10.1016/j.resp. 2006. 02.001. PubMed PMID: 16530025.

On PC. Overview of synchronous couch Am j manag care. 2022; 28 (9 Suppl): s152-s8 Epub 2022/10/06. doi: 10.37765/ ajmc.2022.89243. PubMed PMID: 36198073.

Xiao D, Chen Z, Wu s, et al. Prevalence and risk factors of small airway dysfunction, and association with smoking, in china: finding from a national cross-sectional study. lancet respir med. 2020; 8 (11): 1081-93 EPub 2020/07/01. doi: 10.1016/ s2213-2600 (20) 30155-7 PubMed PMID: 32598906.

Song WJ, Hui CKM, Hull JH, et al. Confronting covid-19-associated cough and the post covid syndrome: role of virtual neurotropism, neuroinflammation, and neuroimmune responses. lancet respir med. 2021; 9 (5): 533-44 EPub 2021/ 04/ 16. doi: 10.1016/s2213-2600 (21) 00125-9 PubMed PMID: 33857435.

Morice AH, Jakes AD, Faruqi S, et al. A worldwide survey of chronic cough: a declaration of enhanced somatosensory response. EUR respir J. 2014; 44 (5): 1149-55 Epub 2014/09/ 05. doi: 10.1183/09031936.00217813. PubMed PMID: 2518 6267.

Huang Jinhua, Xu Pusheng, Li jiaowu, et al .Epidemiological investigation of chronic cough without obvious abnormality on chest X-ray. Guangdong Medical University 2017; 38 (10): 1574-7 doi: 10.3969/j.issn.1001-9448.2017.10.029.

Lai K, Long L, Yi F, et al. Age and sex distribution of Chinese chronic cough patients and their relationship with capsaicin cough sensitivity. allergy ashma immune res. 2019; 11 (6): 871-84 Epub 2019/09/26. doi: 10.4168/aair.2019.11.6.871. PubMed PMID: 31552721; PubMed Central PMCID: PMC PMC6761072.

Liang Hanwen, Yi Fang, Chen Yuehan, et al.Current situation and Prospect of epidemiological investigation of chronic cough in China. Chinese Journal of tuberculosis and respiration.2022; 45 (1): 100-6 doi: 10.3760/cma.j.cn112147-20211104-00773.

Meltzer EO, Zeiger RS, Dicpinigaitis P, et al. Prevalence and Burden of Chronic Cough in the United states. J allergy Clin Immunol practice. 2021; 9 (11): 4037-44 e2 Epub 2021/08/02. doi: 10.1016/j.jaip.2021.07.022. PubMed PMID: 34333189.







How to Cite

He, J., Jiang, Z., Xu, F., Zhang, X., Yin, C., Yao, Y., & Huang, J. (2024). Epidemiological Investigation of Chronic Cough in Chongqing. International Journal of Biology and Life Sciences, 6(2), 7-10. https://doi.org/10.54097/zhw9nz57