Active Components and Applications of Ginkgo Biloba Leaves
DOI:
https://doi.org/10.54097/6xex0w48Keywords:
Ginkgo biloba; flavonoids, terpenoids, antioxidant, neuroprotection, cardiovascular diseases.Abstract
The pharmacological relevance of Ginkgo biloba extract lies in its well-characterized composition and broad therapeutic spectrum. This review highlights the biological activities of its principal phytochemicals—flavonoids and terpenoid lactones—emphasizing their roles in oxidative stress reduction, platelet aggregation inhibition, inflammation modulation, and neuroprotection. Clinical utility is supported by both monotherapy and combinatory regimens, especially in cerebrovascular and neurodegenerative conditions. The extract's standardized formulation, EGb 761, demonstrates consistent efficacy and tolerability, though careful consideration is needed regarding anticoagulant interactions. This paper synthesizes current evidence on the compound’s mechanisms of action and practical applications, contributing to a more integrative understanding of plant-based therapeutics.
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