Research and Implementation of Colorectal Cancer Tumour Segmentation Algorithm based on DRA-UNet

Authors

  • Yuqian Wang
  • Aksyonov Sergey Vladimirovich
  • Qilun Li

DOI:

https://doi.org/10.54097/5zw57182

Keywords:

U-Net, Attentional Mechanisms, Depth Residual Structure, Rectal Tumor

Abstract

Fully convolutional neural networks often suffer from information loss and suboptimal accuracy in medical image segmentation tasks. To mitigate these issues for rectal tumor analysis, we propose an improved U-Net architecture, designated as Deep Residual Attention U-Net (DRA-UNet). First, deep residual modules replace the original convolutional blocks. This substitution enhances feature extraction capabilities while mitigating network degradation. secondly, an attention mechanism is added between each jump connection of the U-Net to focus attention on the features useful for segmentation and suppress redundant features; finally, a DiceLoss loss function is used to alleviate the class imbalance problem. Experimental validation was performed on a colorectal cancer CT image dataset, with segmentation performance quantified using the Dice coefficient. The experimental results demonstrate that the proposed method achieves a segmentation accuracy of 91.38% for colorectal cancer tumors. This represents a significant improvement over existing models, with performance gains of 9.08%, 6.61%, and 4.73% compared to the FCN, U-Net, and Dense-UNet frameworks, respectively. These comparative outcomes confirm the effectiveness and superiority of our approach.

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References

[1] F. A. Sinicrope, "Increasing incidence of early-onset colorectal cancer," New England Journal of Medicine, vol. 386, no. 16, pp. 1547-1558, 2022. DOI: [10.1056/NEJMra2200869] (https:// doi.org/ 10. 1056/ NEJMra2200869).

[2] R. L. Siegel, K. D. Miller, A. G. Sauer, et al., "Colorectal cancer statistics," CA: A Cancer Journal for Clinicians, vol. 70, no. 3, pp. 145-164, 2020. DOI: [10.3322/caac.21601] (https:// doi.org/ 10. 3322/ caac. 21601).

[3] F. T. Kolligs, "Diagnostics and epidemiology of colorectal cancer," Visceral Medicine, vol. 32, no. 3, pp. 158-164, 2016. DOI: [10.1159/000446488](https://doi.org/10.1159/000446488).

[4] J. Dong, T. S. Ma, Y. H. Xu, et al., "Characteristics and potential malignancy of colorectal juvenile polyps in adults: a single-center retrospective study in China," BMC Gastroenterology, vol. 22, no. 1, p. 256, 2022. DOI: [10.1186/s12876-022-02564-8](https://doi.org/10.1186/s12876-022-02564-8).

[5] M. Bretthauer, M. Løberg, P. Wieszczy, et al., "Effect of colonoscopy screening on risks of colorectal cancer and related death," New England Journal of Medicine, vol. 387, no. 17, pp. 1547-1556, 2022. DOI: [10.1056/NEJMoa2208375] (https://doi.org/10.1056/NEJMoa2208375).

[6] Y. Lecun, L. Bottou, Y. Bengio, et al., "Gradient-based learning applied to document recognition," Proceedings of the IEEE, vol. 86, no. 11, pp. 2278-2324, 1998. DOI: [10.1109/5. 726791] (https:// doi. org/ 10.1109/5.726791).

[7] K. Trebing, T. Stańczyk, and S. Mehrkanoon, "SmaAt-UNet: Precipitation nowcasting using a small attention-UNet architecture," Pattern Recognition Letters, vol. 145, pp. 178-186, 2021. DOI: [10. 1016/ j. patrec. 2021.01.027] (https://doi.org/10.1016/j.patrec.2021.01.027).

[8] M. M. Van Heeswijk, D. M. J. Lambregts, J. J. M. Van Griethuysen, et al., "Automated and semiautomated segmentation of rectal tumor volumes on diffusion-weighted MRI: can it replace manual volumetry?" International Journal of Radiation Oncology Biology Physics, vol. 94, no. 4, pp. 824-831, 2016. DOI: [10. 1016/j.ijrobp.2015.12.017](https://doi.org/10.1016/j.ijrobp.2015.12.017).

[9] M. H. Soomro, G. Giunta, A. Laghi, et al., "Segmenting MR images by level-set algorithms for perspective colorectal cancer diagnosis," in Proceedings of the 2017 European Congress on Computational Methods in Applied Sciences and Engineering, 2017, pp. 396-406. DOI: [10.1016/j. phro. 2022. 05.001] (https://doi.org/10.1016/j.phro.2022.05.001).

[10] Z. Ran, J. M. Jian, M. M. Wang, et al., "Automatic segmentation method based on full convolution neural network for rectal cancer tumors in magnetic resonance image," Beijing Biomedical Engineering, vol. 38, no. 5, pp. 465-471, 2019.

[11] O. Ronneberger, P. Fischer, and T. Brox, "U-Net: Convolutional networks for biomedical image segmentation," in Proceedings of the International Conference on Medical Image Computing and Computer-Assisted Intervention, 2015, pp. 234-241. DOI: [10.1007/978-3-319-24574-4_28](https: //doi. org/ 10.1007/978-3-319-24574-4_28).

[12] J. Wang, J. Lu, G. Qin, et al., "Technical note: A deep learning-based auto segmentation of rectal tumors in MR images," Medical Physics, vol. 45, no. 5, pp. 2560-2564, 2018. DOI: [10.1002/ mp. 12887] (https: //doi. org/10.1002/mp.12887).

[13] O. Oktay, J. Schlemper, L. L. Folgoc, et al., "Attention U-Net: Learning where to look for the pancreas," arXiv preprint arXiv:1804.03999, 2018. [Online]. Available: [https://arxiv.org/ abs/1804. 03999] (https: // arxiv.org/abs/1804.03999).

[14] K. He, X. Zhang, S. Ren, et al., "Deep residual learning for image recognition," in Proceedings of the IEEE Conference on Computer Vision and Pattern Recognition, 2016, pp. 770-778. DOI: [10.1109/ CVPR. 2016. 90] (https://doi.org/10.1109/CVPR.2016.90).

[15] A. Kaku, C. Hegde, J. Huang, et al., "Darts: DenseUnet-based automatic rapid tool for brain segmentation," 2019. [Online]. Available: https://arxiv.org/abs/1911.05567.

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Published

27-11-2025

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