The Mechanism and Coping Strategies of Sleep Disturbance during Perimenopause

Authors

  • Leyi Su

DOI:

https://doi.org/10.54097/p3xr3a58

Keywords:

Sleep disturbance; Perimenopause; Estrogen; Progesterone.

Abstract

Many women suffer from menopausal symptoms, especially the sleep disturbances, which is harmful to health and living standard. This review aims to provide the information about mechanism of how lacking estrogen and progesterone affects the sleeping quality. Estrogen can control body temperature, regulation of cortisol and depression and progesterone have impact on nervous system and breathing. Those impacts play pivotal role in sleeping quality, so that understanding the mechanism is extremely useful for establishing effective treatment. Also, the review provides the corresponding treatment, including hormone therapy, CBTI, and aerobic exercise. Overall, hormone therapy supplies the deficient hormone directly, which is the most effective method for treating perimenopausal sleep disorders, CBTI is a non-pharmacological approach, and aerobic exercise offers additional benefits for sleep and general health. Further research is warranted to compare the results of different treatments in the long term and to make some plans for more Individualized treatment which can be more effective and lead to better outcomes.

Downloads

Download data is not yet available.

References

[1] Troìa L, Garassino M, Volpicelli AI, Fornara A, Libretti A, Surico D, Remorgida V. Sleep Disturbance and Perimenopause: A Narrative Review. J Clin Med. 2025 Feb 23;14(5):1479. doi: 10.3390/jcm14051479. PMID: 40094961; PMCID: PMC11901009.

[2] Baker FC, Siboza F, Fuller A. Temperature regulation in women: Effects of the menstrual cycle. Temperature (Austin). 2020 Mar 22;7(3):226-262. doi: 10.1080/23328940.2020.1735927. PMID: 33123618; PMCID: PMC7575238.

[3] Eichling, P. S., & Sahni, J. (2005). Menopause related sleep disorders. Journal of Clinical Sleep Medicine, 1(3), 291–300. https://doi.org/10.5664/jcsm.26347

[4] McCarley RW. REM sleep and depression: common neurobiological control mechanisms. Am J Psychiatry. 1982 May;139(5):565-70. doi: 10.1176/ajp.139.5.565. PMID: 6122380.

[5] Pan Z, Wen S, Qiao X, Yang M, Shen X, Xu L. Different regimens of menopausal hormone therapy for improving sleep quality: a systematic review and meta-analysis. Menopause. 2022 May 1;29(5):627-635. doi: 10.1097/GME.0000000000001945. PMID: 35102100; PMCID: PMC9060837.

[6] Drake CL, Kalmbach DA, Arnedt JT, Cheng P, Tonnu CV, Cuamatzi-Castelan A, Fellman-Couture C. Treating chronic insomnia in postmenopausal women: a randomized clinical trial comparing cognitive-behavioral therapy for insomnia, sleep restriction therapy, and sleep hygiene education. Sleep. 2019 Feb 1;42(2):zsy217. doi: 10.1093/sleep/zsy217. PMID: 30481333; PMCID: PMC6369725.

[7] Jing Y, Liu M, Tang H, Kong N, Cai J, Yin Z. The effect of aerobic exercise on sleep disorder in menopausal women: a systematic review and meta-analyses. BMC Womens Health. 2024 Dec 4;24(1):635. doi: 10.1186/s12905-024-03477-2. PMID: 39627770; PMCID: PMC11616110.

Downloads

Published

28-12-2025

Issue

Section

Articles

How to Cite

Su, L. (2025). The Mechanism and Coping Strategies of Sleep Disturbance during Perimenopause. Academic Journal of Science and Technology, 18(1), 687-691. https://doi.org/10.54097/p3xr3a58