Visualized Detection of NQO 1 Point Mutations in the Liver Cancer Gene Using AuNP-DNA Probes based on a Plasmon Nanosensor Nucleic Acid Detection System

Authors

  • Shuhuang Chen

DOI:

https://doi.org/10.54097/ijbls.v4i1.20

Keywords:

Liver Cancer, NQO 1 Gene, Plasma, Biosensor, AuNP Probe

Abstract

Plasmonic nanobiosensor is an optical biosensor based on the localized surface plasmon resonance effect (LSPR) of metal nanoparticles. This article mainly introduces the use of plasma nanosensor nucleic acid detection system of AuNP-DNA as nucleic acid probe for liver cancer expression related gene NQO 1 point mutation visual detection, and discusses the plasma nano biosensor compared with the traditional advantages of liver cancer early screening method and broad application prospects, and in the formation of liver cancer or liver cancer diagnosis and treatment in the field of timely treatment and prevention play an important role in advance.

Downloads

Download data is not yet available.

References

Cai, Z (2021) Promote new standards to solve the problem of diagnosis and treatment of liver cancer National Health Commission "Diagnosis and Treatment of Primary liver cancer". The Doctor Newspaper, 3.

Wang, X., Cui, F., Zhang, X. (2022) Liver cancer: Early screening "this string". Medical and Health Science and Technology, 2.

Fan, R., Chen, L., Du, Y., et al. (2021) Expert consensus on early screening strategy for liver cancer in China. Medical and Health Science and Technology, 825-831.

Yang, H., Yuen, M., Chan, H., et al. (2011) Risk estimation for hepatocellular carcinoma in chronic hepatitis B(REACH-B): Development and validation of a predictive score. I ancet Oncol., 12: 568-574.

Zhang, H., Zhu, J., Xi, L., et al. (2019) Validation of the Toronto hepatocellular carcinoma risk index for patients with cirrhosis in China: a retrospective cohort study. World J Surg Oncol., 17: 75.

Chen, L., Abou-Alfa, G.K., Zheng, B., et al. (2021) Genomescale profiling of circulating cel-free DNA signatures for early detection of hepatocellular carcinoma in cirrhotic patients. Cell Res., 31: 589-592.

Tzartzeva, K., Obi, J., Rich, N.E., et al. (2018) Surveillance imaging and alpha fetoprotein for early detection of hepatocellular carcinoma in patients with cirrhosis: a meta-analysis. Gastroenterology, 154:1706-1718.

Li, X. (2022) Development of plasma nanobiosensors and their research progress in pathogenic microorganism detection Figure Classification. Journal of Guangdong Medical University, 250-258.

Wang, H., Zheng, X., Sun, Y., et al. (2023) Small molecules detection by SPR sensor. Journal of Qilu University of Technology, 37-44.

Bioengineering Institute of Military Medicine, Academy of Military Sciences. (2019) Rapid detection method of H5N1 influenza virus based on SPR biosensor Classification number. Journal of China Agricultural University, 76-81.

Wang, H., Lin, L. (2022) Prognostic evaluation significance of NQO 1 expression in hepatocellular carcinoma Middle Figure Classification. Journal of Clinical and Experimental Pathology, 658-662+668.

Xia, X., Jin, Z. (2002) Classification number of NQO 1 enzyme and its expression induced by oxygen environment. Advances in Physiological Science, 225-229.

Wang, X. (2022) NQO 1 regulates the mechanism of the malignant evolution of liver cancer through SREBP1-mediated lipid metabolism. Medical and Health Science and Technology, 96.

Downloads

Published

15-11-2023

Issue

Section

Articles

How to Cite

Chen, S. (2023). Visualized Detection of NQO 1 Point Mutations in the Liver Cancer Gene Using AuNP-DNA Probes based on a Plasmon Nanosensor Nucleic Acid Detection System. International Journal of Biology and Life Sciences, 4(1), 76-78. https://doi.org/10.54097/ijbls.v4i1.20