Effectiveness of Femtosecond Laser Combined with Recombinant Human Epidermal Growth Factor in Postoperative Dry Eye in Cataract Patients and Effect on Ocular Surface Function

Rui Ding; Lijun Yang

doi:10.54097/zkv7jx03

Authors

Rui Ding
Lijun Yang

DOI:

https://doi.org/10.54097/zkv7jx03

Keywords:

Femtosecond Laser, Recombinant Human Epidermal Growth Factor, Cataracts, Postoperative Dry Eye, Ocular Surface Function

Abstract

Sixty patients with dry eye after cataract surgery admitted to Lanzhou Purui Optometry Hospital from January 2023 to February 2024 were selected as the study subjects, and were divided into observation group (30 cases) and control group (30 cases) according to the envelope method, with femtosecond laser treatment for the patients in the control group, and combined treatment with recombinant human epidermal growth factor for the patients in the observation group. The Ocular Surface Disease Index OSDI questionnaire (assessing ocular surface function), Dry Eye Symptom Assessment Questionnaire, Fluorescein Staining Score, FL Score, Tear Secretion Test (SIT), Tear Film Stability Test (BUT) and safety were compared between the two groups. The OSDI questionnaire score, dry eye symptom assessment questionnaire and fluorescein staining score of the observation group were lower than those of the control group after the intervention, and the difference was statistically significant (P < 0.05); the FL score of the observation group was lower than those of the control group, and the difference was statistically significant (P < 0.05); the SIT and BUT of the observation group were higher than those of the control group, and the difference was statistically significant (P < 0.05); the adverse reaction rate of the patients in both groups was compared. The incidence of adverse reactions in the two groups was not statistically significant (P>0.05). Conclusion: Femtosecond laser combined with recombinant human epidermal growth factor in patients with dry eye after cataract surgery can help to improve the patients' ocular surface function, can reduce fluorescein staining, SIT and BUT levels, and has high therapeutic safety, which is worthy of popularization and application.

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