The Valuation and Strategic Role of Amgen as an Anchor Stock in the Biopharmaceutical Industry Under Market Volatility
DOI:
https://doi.org/10.54097/am35dd94Keywords:
Anchor stock, valuation, NTM P/E, PEG ratio, GP/A.Abstract
The research implements a scientific method for choosing anchor stocks and determining their value in the U.S. biopharmaceutical industry through a case study of Amgen. The research evaluates Amgen’s intrinsic value by analyzing three financial metrics including NTM P/E ratio and PEG ratio and GP/A ratio and performs a peer analysis with Gilead Sciences, Biogen and Regeneron to assess competitive advantages and disadvantages. The analysis reveals that Amgen provides diversified therapeutic exposure and stable cash flows and consistent dividends which makes it a defensive growth investment that matches the Growth at a Reasonable Price (GARP) profile. The company faces three main challenges which include biosimilar competition, margin pressures and regulatory changes from the Inflation Reduction Act, and increased R&D expenses. The valuation analysis indicates possible moderate price appreciation which depends on successful late-stage pipeline development and margin improvement. The research establishes theoretical evidence for selecting anchor stocks during market volatility while offering practical methods to build investment portfolios that unite stability with growth potential in biopharmaceuticals.
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[1] Liu, S., et al. Market volatility and anchor stock selection. Journal of Finance and Investment, 2021, 45(3): 122–135.
[2] Brown, D., Smith, J. Portfolio construction under uncertainty. Financial Analysts Journal, 2021, 77(5): 88–102.
[3] Petersen, M. R. Complexity in stock valuation. Review of Financial Studies, 2021, 34(2): 451–477.
[4] Yamamoto, K., et al. Innovation drivers in the US biopharmaceutical industry. Nature Reviews Drug Discovery, 2022, 21(7): 501–515.
[5] Andrews, T. Competitive positioning in oncology and immunology. Pharmaceutical Strategy Review, 2023, 18(1): 14–29.
[6] Martinez, E., Li, C. Regulatory risks in biopharma R&D. Health Economics, 2023, 32(4): 789–804.
[7] Roberts, P., et al. Valuation of biotech firms. Journal of Applied Corporate Finance, 2022, 34(2): 65–78.
[8] Nguyen, A. Anchor stock selection criteria. Investment Science Review, 2021, 10(2): 99–115.
[9] Chen, R., et al. Financial ratios in biotech valuation. Accounting and Finance Research, 2023, 12(1): 33–50.
[10] Patel, J., Wong, S. Peer analysis in pharmaceutical markets. Strategic Management Journal, 2023, 44(5): 923–940.
[11] Kim, L. Investment frameworks for biotech. Journal of Portfolio Management, 2023, 49(4): 77–92.
[12] Hall, M. Risk factors in biotech investing. Finance Research Letters, 2022, 47(4): 103024.
[13] Smith, G., et al. Global healthcare market volatility. Health Policy and Economics, 2021, 31(3): 345–360.
[14] Zhou, B., Williams, T. Revenue uncertainty in biopharma. Journal of Business Research, 2021, 137: 215–227.
[15] Zhang, F., et al. Scale economies in biotech resilience. Industrial Organization Review, 2022, 39(1): 66–81.
[16] EvaluatePharma. World Preview 2024, Outlook to 2030. London, UK: Evaluate Ltd., 2024.
[17] Costa, A. Financial strength and stock stability. Journal of Investment Strategies, 2022, 12(2): 145–160.
[18] Amgen Inc. Annual Report 2024. Thousand Oaks, CA: Amgen Inc., 2025.
[19] Wong, S., Lee, J. Diversification benefits in biotech. Biotechnology Economics Journal, 2022, 11(2): 201–215.
[20] Harrison, D., et al. Market disruptions in pharma. Pharmaceutical Market Journal, 2021, 16(3): 77–90.
[21] Gilead Sciences Inc. Annual Report 2024. Foster City, CA: Gilead Sciences Inc., 2025.
[22] Ross, T., et al. Antiviral drug market risks. Virology Market Review, 2023, 8(1): 55–68.
[23] Biogen Inc. Annual Report 2024. Cambridge, MA: Biogen Inc., 2025.
[24] Regeneron Pharmaceuticals Inc. Annual Report 2024. Tarrytown, NY: Regeneron Pharmaceuticals Inc., 2025.
[25] FactSet. FactSet Research Systems Inc. Database. Norwalk, CT: FactSet Research Systems Inc., Aug. 2025.
[26] EvaluatePharma. EvaluatePharma World Preview 2025, Outlook to 2030. London, UK: Evaluate Ltd., 2025.
[27] Stone, M. Dividend policies in biotech. Corporate Finance Journal, 2022, 15(4): 198–212.
[28] FactSet. Biopharmaceutical Valuation Data. Norwalk, CT: FactSet Research Systems Inc., Aug. 2025.
[29] Klein, J., et al. P/E ratios and biotech growth. Financial Markets Review, 2022, 14(2): 77–92.
[30] Thompson, L. Growth premiums in large-cap biotech. Journal of Financial Economics, 2022, 146(3): 641–658.
[31] IQVIA. Medicare Drug Price Negotiation Impact. Durham, NC: IQVIA, 2024.
[32] EvaluatePharma. World Preview 2025, Outlook to 2030. London, UK: Evaluate Ltd., 2025.
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