Advances of biology sorter based on laminar flow
DOI:
https://doi.org/10.54097/hset.v58i.10098Keywords:
biology sorter, laminar flow, H-Filter, Spiral channel sorter.Abstract
Now the biological sorters are widely applied in biology and medicine to separate specific sample. Each kind of the sorters are fitting different kind of situations and having a large difference between their cost, efficiency and other factor. In order to help researchers to find a suitable bio-sorters for their research, in this paper, four kind of passive bio-sorters that based on laminar flow were introduced, and their strengths and limitations were discussed. They share common strengths, such as simple design, low cost and so on. These makes them easy to be generalized and applied. Some possible improvements of the sorters were proposed, such as more detailed channels and external electromagnetic field to make the result more efficiency.
Downloads
References
Shen, Y., Yalikun, Y., Tanaka, Y. (2018) Recent advances in microfluidic cell sorting systems. https://doi.org/10.1016/j.snb.2018.11.025.
Encyclopædia Britannica, inc. (n.d.). (2018) Laminar flow. https://www.britannica.com/science/laminar-flow.
Herzenberg, L.A., Parks, D., Sahaf, B., Perez, O., Roederer, M., Herzenberg, L.A. (2002) The history and future of the fluorescence activated cell sorter and flow cytometry, A view from Stanford. Clin. Chem. 48: 1819 – 1827.
Hulett, H.R., Bonner, W.A., Barrett, J., Herzenberg, L.A. (1969) Cell sorting: automated separation of mammalian cells as a function of intracellular fluorescence. Science 166: 747 – 749.
Gossett, D.R., Weaver, W.M., Mach, A.J., Hur, S.C., Tse, H.T.K., Lee, W., Amini, H., Di Carlo, D. (2010) Label-free cell separation and sorting in microfluidic systems. Anal. Bioanal. Chem. 397: 3249 – 3267.
Bhagat, A. A. S., Bow, H., Hou, H. W., Tan, S. J., Han, J., & Lim, C. T. (2010) Microfluidics for Cell separation. https://link.springer.com/article/10.1007/s11517-010-0611-4.
Carlo, D. D., Irimia, D., Tompkins, R. G., & Toner, M. (2007) Continuous inertial focusing, ordering, and separation of particles in microchannels. PNAS. https://www.pnas.org/content/104/48/18892.
Carlo, D. D. (2009) Inertial microfluidics. Lab on a Chip. https://pubs.rsc.org/en/content/articlelanding/2009/lc/b912547g.
Cho, B. S., Schuster, T. G., Zhu, X., Chang, D., Smith, G. D., & Takayama, S. (2003) Passively driven integrated microfluidic system for separation of motile sperm. ACS Publications. https://pubs.acs.org/doi/10.1021/ac020579e.
Nilsson, A., Petersson, F., Jonsson, H., and Laurell, T. (2004) Lab Chip 4: 131 – 135.
Nyborg, W. L. (1978) in Ultrasound: Its Applications in Medicine and Biology, ed. F. J. Fry, Elsevier, New York, Part 1, pp. 1 – 76.
Petersson, F., Nilsson, A., Holm, C., Jönsson, H., & Laurell, T. (2004) Separation of lipids from blood utilizing ultrasonic standing waves in microfluidic channels. https://pubs.rsc.org/en/content/articlelanding/2004/an/b409139f.
Klodell, C. T., Richardson, J. D., Berdamini, T. M. and D. A. Spain, Am. Surg. (2001) 67(1): 44 - 47.
Shen, S., Tian, C., Li, T., Xu, J., Chen, S.-W., Tu, Q., Yuan, M.-S., Liu, W., & Wang, J. (2017) Spiral microchannel with ordered micro-obstacles for continuous and highly-efficient particle separation. Lab on a Chip. https://pubs.rsc.org/en/content/articlelanding/2017/lc/c7lc00691h.
Downloads
Published
Issue
Section
License

This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.







