Research Progress of Cancer Vaccine
DOI:
https://doi.org/10.54097/0bw4mz12Keywords:
Cancer; Preventive Vaccines; Cancer Treatment Vaccines; Cancer Immunotherapy.Abstract
Cancer has now become the major cause of pre-mature death around the world. In the past decades, research on tumor immunotherapy has advanced significantly, with numerous studies being evaluated in the clinical setting. The cancer vaccine is regarded as an advantageous approach in the immunotherapy of solid tumors. Preventive cancer vaccines can be injected in advance to reduce the risk of having cancer, while therapeutic vaccines can be used to trigger immunoresponse after having cancer. For example, recent studies have found that vaccination with one or more doses of the HPV vaccine produces more than 90 percent effective protection. In the meantime, the best and safest way to prevent hepatitis B is to get the hepatitis B vaccine. This paper introduces the mechanisms of both two types of cancer vaccines, and focuses on the explanation of the two cancer vaccine therapies. As a systematic review, it also highlights their current states and possible future improvements.
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References
Iarc,“Cancer Today.”, 2018, gco.iarc.fr/today/fact-sheets-cancers.
Igarashi, Yuka, and Tetsuro Sasada. “Cancer Vaccines: Toward the next Breakthrough in Cancer Immunotherapy.” Journal of Immunology Research, edited by Fabiano Carvalho, vol. 2020, Nov. 2020, pp. 1–13,
Martins, Filipe, et al. “Adverse Effects of Immune-Checkpoint Inhibitors: Epidemiology, Management and Surveillance.” Nature Reviews Clinical Oncology, vol. 16, no. 9, May 2019, pp. 563–80
Brenner, Hermann, et al. “Helicobacter Pylori Infection among Offspring of Patients with Stomach Cancer.” Gastroenterology, vol. 118, no. 1, Jan. 2000, pp. 31–35.
World Health Organization. “How Do Vaccines Work?” Www.who.int, 8 Dec. 2020, www.who.int/news-room/feature-stories/detail/how-do-vaccines-work.
Pulendran, et al. “Immunological Mechanisms of Vaccination.” Nature Immunology, vol. 12, no. 6, May 2011, pp. 509–17.
Office of Infectious Disease and HIV/AIDS Policy (OIDP). “Vaccine Types.” HHS.gov, 22 Dec. 2022, www.hhs.gov/immunization/basics/types/index.html.
“Inactivated Vaccines - Latest Research and News | Nature.” Www.nature.com, www.nature.com/subjects/inactivated-vaccines.
“Toxoid - an Overview | ScienceDirect Topics.” Www.sciencedirect.com, www.sciencedirect.com/topics/medicine-and-dentistry/toxoid.
Kashyap, et al. “Outer Membrane Vesicles: An Emerging Vaccine Platform.” Vaccines, vol. 10, no. 10, Sept. 2022, p. 1578
Micoli, Francesca, and Calman A. MacLennan. “Outer Membrane Vesicle Vaccines.” Seminars in Immunology, vol. 50, Aug. 2020, p. 101433.
Kamolratanakul, et al. “Human Papillomavirus Vaccine Efficacy and Effectiveness against Cancer.” Vaccines, vol. 9, no. 12, Nov. 2021, p. 1413.
Pathak, Pranav, et al. “A Review on the Use of the HPV Vaccine in the Prevention of Cervical Cancer.” Cureus, vol. 14, no. 9, Sept. 2022.
Center for Biologics Evaluation and Research. “Vaccines Licensed for Use in the US.” U.S. Food and Drug Administration, 2019, www.fda.gov/vaccines-blood-biologics/vaccines/vaccines-licensed-use-united-states.
Garland, et al. “Impact and Effectiveness of the Quadrivalent Human Papillomavirus Vaccine: A Systematic Review of 10 Years of Real-World Experience.” Clinical Infectious Diseases, vol. 63, no. 4, May 2016, pp. 519–27.
Vaccines: VPD-VAC/HepB/Main Page. 2019, www.cdc.gov/vaccines/vpd/hepb/index.html. Accessed 1 Sept. 2023.
Liu, Jian, et al. “Cancer Vaccines as Promising Immuno-Therapeutics: Platforms and Current Progress.” Journal of Hematology & Oncology, vol. 15, no. 1, Mar. 2022.
“Sipuleucel-T - NCI.” Www.cancer.gov, 28 June 2010, www.cancer.gov/about-cancer/treatment/drugs/sipuleucel-t#SnippetTab.
“Https://Www.cancer.gov/About-Cancer/Treatment/Clinical-Trials/Intervention/Sipuleucel-t?Redirect=True.” Www.cancer.gov, 13 June 2017, www.cancer.gov/about-cancer/treatment/clinical-trials/intervention/sipuleucel-t?redirect=true.
“Cancer Vaccines | Memorial Sloan Kettering Cancer Center.” Www.mskcc.org, www.mskcc.org/cancer-care/diagnosis-treatment/cancer-treatments/immunotherapy/cancer-vaccines.
Hollingsworth, et al. “Turning the Corner on Therapeutic Cancer Vaccines.” Npj Vaccines, vol. 4, no. 1, Feb. 2019
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