Biological characteristics of NK cells and their application in cancer treatment

Abstract

The leading cause of mortality among people is cancer. Traditional medicine, however, has significant dangers and negative effects. Because of its great effectiveness, lack of side effects, and safety, cellular immunotherapy has been utilized extensively in the treatment of malignancies in recent years. While various treatment options have many benefits, they also present unique issues and difficulties. In certain ways, NK cell immunotherapy can make up for these deficiencies. It is not necessary to rely on the patient's distinct immune cells because they may be made from allogeneic cells. Additionally, it can successfully cure the majority of solid tumours, get rid of cancer cells that are resistant to chemotherapy and radiation treatment and metastasis, and enhance the body's immune system, which is the present study's emphasis. As a result, this article begins by introducing the basic traits of NK cells, including traits, uses, activation methods, and how NK cells destroy other cells in an immune response. The use of NK cell therapy in treating different cancers, including hematological malignancies, is then emphasized. Finally, NK cell treatment for cancer development and potential issues are examined. In the future, it will serve as a reference for the treatment of tumours.