Comparative Analysis of Microsatellite Sequences in Six Gamma-coronaviruses
DOI:
https://doi.org/10.54097/rrcvhv94Keywords:
γ-coronavirus, Simple repeat sequences, Microsatellites, Comparative analysis of microsatellitesAbstract
Microsatellite sequences are DNA or RNA repeat sequences with 1-6 bases as repeat units, also known as simple repeat sequences, that appear in the genome's non-coding, coding, and intergenic regions. Microsatellite sequences are extremely changeable and varied, and their presence encourages genomic variety and evolution. Gamma-coronavirus is a genus in the Coronaviridae subfamily. Microsatellites are extensively dispersed in gamma-coronavirus genomes' coding and non-coding regions. There are currently few papers on the microsatellite analysis of γ-coronaviruses. The distribution frequency, GC content, and nucleotide repeat sequences of γ-coronavirus SSR were studied in this work using MISA online program and SSRhunter, and three results were drawn: 1.Viruses have a short evolutionary period and a lower variety of microsatellites than prokaryotes and eukaryotes. 2.Type II microsatellites have a significant role in cross-species infection and gene expression differences. 3.Evolution might be skewed. This research will contribute to a better understanding of the structure, function, and evolutionary importance of microsatellites in tiny genomes.
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