Action Mechanism and Side Effects of Tetrodotoxin
DOI:
https://doi.org/10.54097/3qqc8269Keywords:
Tetrodotoxin, Action mechanism, Side effects.Abstract
Tetrodotoxin (TTX) is one of the most toxic neuro-toxins found in the world at present. This drug has been widely used in the medical field, such as treating cancer related pain and severe arrhythmias. It is widely distributed and has been found in various high and low organisms such as aquatic and terrestrial organisms. But the source of the TTX and detoxification methods still need to be studied, so the study of the TTX is very significant. At the same time, TTX can block sodium ion channels, has obvious analgesic effect, and also has antiarrhythmia, abandon drug addiction and other effects. As a result, TTX has high medical and commercial value. This research will mainly summarize the pharmacological action, side effects of TTX and its underlying principle. In addition, it is expected that this study can provide new ideas for the study of new functions of TTX and the treatment of new diseases.
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