Application of Cell Membrane-Coated Nanoparticles in the Medical Field
DOI:
https://doi.org/10.54097/6693qm86Keywords:
Cell membrane, nanoparticles, cell membrane coating technology, medical field.Abstract
Since the advent of nanotechnology, nanomaterials have found extensive application in the medical industry. The application of nanoparticles is currently constrained by their low biosafety, limited blood circulation period, and poor targeting capacity. Cell membranes have been continually replicated and employed for encapsulation and camouflage of nanoparticles, to improve their biological features. Cell membranes serve as a window and interface for communication within the human body. Nanomedicine has recently advanced to a new level of development thanks to coating technology that completely grafts cell membranes onto the surface of nanoparticles. The nanoparticles' cover helps them adapt better to challenging physiological settings. They considerably improve their targeting capabilities and avoid immune system clearance through homologous recognition, broadening their spectrum of applications in drug transportation, biological detoxification, and other fields. This article mainly introduces the research progress of the emerging nanoprobe technology of cell membrane packages, as well as the preparation pathway of cell membrane wrapped nanoparticles and the analysis and research of the application value and development prospects in the med.
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References
Ran, J., et al., "Microreactor-based micro/nanomaterials: fabrication, advances, and outlook," Materials Horizons 10, 2343-2372 (2023).
Wang H., et al., " Cell membrane biomimetic nanoparticles for inflammation and cancer targeting in drug delivery," Biomaterials Science 8, 552-568 (2020).
Carla J., et al., " Nanoparticles coated with cell membranes for biomedical applications," Materials Horizons 9 (11), 406 (2020).
Zhen X, et al., "Recent advances in cell membrane-camouflaged nanoparticles for cancer phototherapy," Small 15 (1), 1804105 (2019).
Sahil M., et al., " Red blood cells membrane-derived nanoparticles: Applications and key challenges in their clinical translation," WIREs Nanomedicine and Nanobiotechnology 14 (3), e1776 (2022).
Wang F., et al., " Endothelial cell membrane-based biosurface for targeted delivery to acute injury: analysis of leukocyte-mediated nanoparticle transportation," Nanoscale 13, 14636-14643 (2021).
Xu L., et al., " Cancer cell membrane-coated nanocarriers for homologous target inhibiting the growth of hepatocellular carcinoma," Journal of Bioactive and Compatible Polymers (2018).
Xiao J., et al., “Red blood cell membrane-coated silica nanoparticles codelivering DOX and ICG for effective lung cancer therapy,” ACS Omega 5 (51), 32861-32867 (2020).
Bu L., et al., “Cancer stem cell-platelet hybrid membrane-coated magnetic nanoparticles for enhanced photothermal therapy of head and neck squamous cell carcinoma,” Advanced Functional Materials 29 (10), 1807733 (2019).
Zhen B., et al., “Red blood cell membrane nanoparticles for tumor phototherapy,” Colloids and Surfaces B: Biointerfaces 220, 112895 (2022).
Gong P., et al., “Immunocyte membrane-coated nanoparticles for cancer immunotherapy,” Cancers 13 (1), 77 (2021).
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