Evaluative Comparison of Machine Learning Algorithms for Precision Diagnosis in Breast Cancer

Authors

  • Jiarui Li

DOI:

https://doi.org/10.54097/40fmfw48

Keywords:

Breast cancer; machine learning; support vector machine; logistic regression; area under the curve values

Abstract

Breast cancer remains a prominent issue in worldwide public health, exhibiting a gender disparity that primarily impacts women. This study systematically evaluates the diagnostic capabilities of various machine learning algorithms in predicting breast cancer recurrences. Utilising a dataset of 569 data points, the algorithms scrutinised include Artificial Neural Networks (ANN), Support Vector Machines (SVM), Decision Trees (DT), Random Forests (RF), XGBoost (XGB), Logistic Regression (LR), and K-Nearest Neighbours (KNN). Principal Component Analysis (PCA) was applied and employed with the algorithmic evaluation for selecting features and reducing dimensionality. The study utilised multiple evaluative metrics, focusing on Receiver Operating Characteristic (ROC) curves and Area Under the Curve (AUC) values. The findings suggest that Logistic Regression and Support Vector Machines performed better than the other algorithms. Specifically, Logistic Regression achieved an AUC value of 99.77%, and Support Vector Machines achieved an AUC value of 99.74%. Additionally, these algorithms demonstrated an accuracy rate of 97.37%, precision of 97.62%, recall of 95.35%, F1 score of 96.47%, and Cohen's Kappa coefficient of 94.37%, consistent. The study suggests potential avenues for further investigation into the utility of machine learning algorithms and dimensionality reduction techniques in diagnosing breast cancer recurrence. These preliminary findings have the potential to make a valuable contribution to the current discourse around the use of machine learning technologies within healthcare environments

Downloads

Download data is not yet available.

References

Bray F, Ferlay J, Soerjomataram I, Siegel RL, Torre LA, Jemal A. Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA Cancer J Clin. 2018 Nov;68(6):394-424.

Breast cancer. 2023, July 12. Breast Cancer. https://www.who.int/news-room/fact-sheets/detail/breast-cancer

Rashmi R, Prasad K, Udupa C B K. Breast histopathological image analysis using image processing techniques for diagnostic purposes: A methodological review. Journal of Medical Systems. 2021, December 3; 46(1).

Esteva A, Robicquet A, Ramsundar B, Kuleshov V, DePristo M, Chou K, Cui C, Corrado G, Thrun S, Dean J. A guide to deep learning in healthcare. Nat Med. 2019 Jan; 25(1):24-29.

Schmidhuber J. Deep learning in neural networks: An overview. Neural networks. 2015; 61: 85-117.

Wolberg William, Mangasarian Olvi, Street Nick, Street W. Breast Cancer Wisconsin (Diagnostic). UCI Machine Learning Repository. 1995.

Heaton J. Ian Goodfellow, Yoshua Bengio, and Aaron Courville: Deep learning. Genetic Programming and Evolvable Machines. 2017, October 29; 19(1–2): 305–307.

Dong S, He D, Zhang Q, Huang C, Hu Z, Zhang C, Nie L, Wang K, Luo W, Yu J, Tian B, Wu W, Chen X, Wang F, Hu J, Xiao X. Early cancer detection by serum biomolecular fingerprinting spectroscopy with machine learning. ELight. 2023, July 24; 3(1).

Noble W S. What is a support vector machine? - Nature Biotechnology. Nature. 2006, December 1.

Quinlan J R. Induction of decision trees. Machine Learning. 1986, March; 1(1): 81–106.

Breiman L. Random forests. Machine Learning. 2001; 45(1): 5-32.

Chen T, Guestrin C. XGBoost: A Scalable Tree Boosting System. Proceedings of the 22nd ACM SIGKDD International Conference on Knowledge Discovery and Data Mining. ACM. 2016; pp. 785-794.

Hosmer Jr D W, Lemeshow S, Sturdivant R X. Applied logistic regression. John Wiley & Sons. 2013.

Altman N S. An Introduction to Kernel and Nearest-Neighbor Nonparametric Regression. The American Statistician. 1992, August; 46(3): 175–185.

Jolliffe I T. Principal Component Analysis, Second Edition. Springer Series in Statistics. New York: Springer. 2002.

Magboo V P C, Magboo M S A. Machine Learning Classifiers on Breast Cancer Recurrences. Procedia Computer Science. 2021; 192: 2742–2752.

Downloads

Published

13-03-2024

How to Cite

Li, J. (2024). Evaluative Comparison of Machine Learning Algorithms for Precision Diagnosis in Breast Cancer. Highlights in Science, Engineering and Technology, 85, 354-362. https://doi.org/10.54097/40fmfw48