Precision Nutrition in the Clinical Application of Digestive Tract Malignant Tumor Treatment: Current Status and Prospects

Abstract

Digestive tract malignancies are a major public health problem in China. Currently, precision nutrition has gradually become a key intervention measure in its treatment. However, there are differences in the understanding of its concept and connotation in China and abroad, and clinical application and research are diverse. At present, precision nutrition has made certain progress in the three aspects of digestive tract tumor treatment. For example, research on nutrition assessment and dietary regulation has been carried out in colorectal cancer (CRC), personalized nutrition assessment and intervention timing have been explored in gastric cancer, and multi-omics applications and the effects of non-drug nutrition preparations have also been involved in esophageal cancer. However, there are still many shortcomings in the clinical application of precision nutrition in digestive tract tumors, such as the lack of popularization of individualized nutrition needs assessment, the gap between cost and technical feasibility, and so on. This article analyzes the research in these aspects and provides a new way to improve the nutritional status of patients and lay the foundation for personalized intervention. However, the application of the research at the system level and socioeconomic factors has not been fully explored. In the future, technological innovation, interdisciplinary cooperation, etc., should be emphasized on basic medical research and multidisciplinary integration to improve treatment effects and quality of life. At the same time, there are still problems to be solved, and subsequent research can be strengthened in related directions.