Design of a CMOS Circuit for Generating Electromyography for Diagnosis of ALS
DOI:
https://doi.org/10.54097/hset.v32i.4981Keywords:
ALS, EMG, CMOS, electromyographyAbstract
As a neurological disease, amyotrophic lateral sclerosis (ALS) causes the patients' motor neurons to be damaged to varying degrees, so that they cannot control the muscles, resulting in motor disorders and muscle atrophy. In the diagnosis of ALS, Electromyography (EMG) is the main part. A small electrode delivers a stimulus to a particular part of the nerve and receives a signal at another part of the nerve. At present, the commonly used method to judge nerve injury is to measure its conduction velocity and time. This paper provides an overview of ALS, delves into the details of EMG generation, and provides a practical CMOS circuit for EMG generation. The circuit uses a current mirror to generate a band of electrical stimulation. This design is stable, cheap, and programmable.
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Brooks B R, Miller R G, Swash M, et al. El Escorial revisited: Revised criteria for the diagnosis of amyotrophic lateral sclerosis. Amyotrophic lateral sclerosis and other motor neuron disorders: official publication of the World Federation of Neurology, Research Group on Motor Neuron Diseases, 2000， 1(5) :293-299.
Jackson C E, Kasarskis E J, Miller R G, et al. Practice parameter update: the care of the patient with amyotrophic lateral sclerosis: drug, nutritional, and respiratory therapies (an evidence-based review): report of the Quality Standards Subcommittee of the American Academy of Neurology. Neurology, 2009. 73(15) :1218-1226.
Hudson A J. Amyotrophic lateral sclerosis and its association with dementia, parkinsonism and other neurological disorders: a review. Brain, 1981. 1981(2) :217-247.
Dengler R, G Küther, Konstanzer A, et al. Amyotrophic lateral sclerosis: Macro-EMG and twitch forces of single motor units. Muscle & Nerve, 2010. 13.
Daube J R. Electrodiagnostic studies in amyotrophic lateral sclerosis and other motor neuron disorders. Muscle & Nerve, 2015.23(10) :1488-1502.
Sonoo M, Kuwabara S, Shimizu T, et al. Utility of trapezius EMG for diagnosis of amyotrophic lateral sclerosis. Muscle & Nerve. 2009.
Roeleveld K, Stegeman D F, Vingerhoets H M, et al. Motor unit potential contribution to surface electromyography. Acta Physiol Scand, 2010, 160(2) :175-183.
Hodges P W, Bang H B. 1996 A comparison of computer-based methods for the determination of onset of muscle contraction using electromyography. Electroencephalography & Clinical Neurophysiology, 101(6) :511-519.
Bejanishvili S, Osborne L E, Messenger K, et al. 2005. EMG vagus nerve stimulator artifact. Neurology & Clinical Neurophysiology, 2005(1).
Heinrichs K. Introduction to Surface Electromyography. Journal of athletic training. 1998, 34(1).
Muraoka Y. Development of portable EMG-controlled electrical stimulator. IEEE. Science Conference. 2002.
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