Advances in research on sleep disorders promoting the deterioration of novel coronaviruses

Abstract

Novel coronavirus pneumonia (Corona Virus Disease 2019, COVID-19) is a disease with fever, dry cough and progressive dyspnea as the main manifestations. 2019 novel coronavirus (2019-nCOV) is transmitted by contact transmission. Sleep disorders are linked to novel coronavirus, it not only reduces the life motivation of patients with COVID-19, but increases the burden on the family members who care for patients. Sleep disorder is related to the aggravation of COVID-19 to some extent. Sleep disorders are a significant factor in advance of COVID-19 into the severe disease, and the pathophysiological changes in COVID-19 also contribute to the problem of it. Sleep disorders exacerbate the body's psychological stress promoting decreased immune function, while interfering with the normal exercise of physiological functions of reactive T cells, which have specific defenses against 2019-nCOV can prevent 2019-nCOV from entering the body, so people with sleep disorders infected with 2019-nCOV will have more severe symptoms than those who do not suffer from sleep disorders. Because the link between COVID-19 and sleep disorders is poorly understood by clinicians, this article describes recent research advances on sleep disorders that exacerbate COVID-19 disease, patient sleep status, and treatment options.