Electrophysiological Features of Late-Stage Language Processing in Patients with Schizophrenia

Baichuan Shi

doi:10.54097/hn757q07

Authors

Baichuan Shi

DOI:

https://doi.org/10.54097/hn757q07

Keywords:

Schizophrenia, ERPs, Semantic processing.

Abstract

Language deficits are a prominent feature of schizophrenia. The Event-Related Potentials (ERPs) is a technique used to investigate neural mechanisms of language processing. Most studies suggest ERPs components of late-stage language processing are abnormal in patients with schizophrenia. This study systematically reviews the electrophysiological features of late-stage language processing in patients with schizophrenia. The N400 amplitude in patients with schizophrenia is usually lower than that of normal individuals, and they are unable to effectively integrate semantics. At the same time, the P600/LPC waveforms of the relevant patients show a situation similar to that of the N400. Both reduced amplitudes of the N400, P600, and LPC components and delayed latencies of the N400 and LPC are abnormally delayed in patients with schizophrenia suggest that patients with schizophrenia exhibit systematic impairments in late-stage language processing. This review provides a theoretical basis for further exploration of the EEG characteristics of language processing in patients with schizophrenia.

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