Research Progress of Agaricus blazei Polysaccharide on Blood Sugar in Diabetic Patients

Authors

  • Zibing Wei

DOI:

https://doi.org/10.54097/ijbls.v4i1.11

Keywords:

Diabetes, Agaricus Blazei Polysaccharide, Hpyerglycemic, Mechanism of Action

Abstract

Diabetes is a metabolic infection portrayed by hyperglycemia, including type 1 diabetes and type 2 diabetes, as well as extraordinary twofold diabetes and gestational diabetes, and it will be accompanied by a variety of complications, which will bring great pain to patients. As of now, there are an enormous number of diabetic patients on the planet, and the quantity of diabetic patients is developing quickly, and it has gradually become younger, which has become a very serious public health problem, so how to work on the counteraction and treatment of diabetes is a vital issue. However, one of the major difficulties in the treatment of diabetes is that it can only control the disease, but it cannot be completely cured. Agaricus blazei Murill is a kind of medicinal mushroom. At present, it is found to be rich in many bioactive substances, and it can be used for adjuvant treatment of many diseases. It is also a potential drug to improve the adjuvant treatment of diabetes. If it can stably produce beneficial glucose metabolism such as lowering blood sugar, it will greatly improve the situation of diabetic patients. Therefore, this paper aims to analyze the pathogenesis of diabetes and the existing literature research on Agaricus blazei polysaccharide, and to clarify the specific role of Agaricus blazei polysaccharide in diabetic blood sugar and the related mechanism of Agaricus blazei polysaccharide in improving blood sugar in diabetic patients.

Downloads

Download data is not yet available.

References

Arunachalam, K., Sreeja, P.S., Yang, X. (2022) The Antioxidant Properties of Mushroom Polysaccharides can Potentially Mitigate Oxidative Stress. Beta-Cell Dysfunction and Insulin Resistance, 13:874474.

Roep, B.O., Thomaidou, S., Van Tienhoven, R., et al. (2021) Type 1 Diabetes Mellitus as a Disease of the β-cell (Do not Blame the Immune System?). Nat Rev Endocrinol., 17:150-161.

Khan, M.A.B., Hashim, M.J., King, J.K., et al. (2020) Epidemiology of Type 2 Diabetes - Global Burden of Disease and Forecasted Trends. J Epidemiol Glob Health., 10:107-111.

Khawandanah, J. (2019) Double or Hybrid Diabetes: A Systematic Review on Disease Prevalence, Characteristics and Risk Factors. Nutr Diabetes., 9:33.

Sweeting, A., Wong, J, Murphy, H.R., et al. (2022) A Clinical Update on Gestational Diabetes Mellitus. Endocr Rev., 43:763-793.

Naseri, R., Navabi, S.J., Samimi, Z., et al. (2020) Targeting Glycoproteins as a Therapeutic Strategy for Diabetes Mellitus and Its Complications. Daru., 28:333-358.

Tomic, D., Shaw, J.E., Magliano, D.J. (2022) The Burden and Risks of Emerging Complications of Diabetes Mellitus. Nat Rev Endocrinol., 18:525-539.

Huang, K., El-Seedi, H.R., Xu, B. (2022) Critical Review on Chemical Compositions and Health-promoting Effects of Mushroom Agaricus Blazei Murill. Curr Res Food Sci., 5:2190-2203.

Zhao, R., Yang, F., Bai, Y., et al. (2023) Research Progress on the Mechanisms Underlying Poultry Immune Regulation by Plant Polysaccharides. Front Vet Sci., 10:1175848.

Cheema, S., Abraham, A., El-Nahas, K.G., et al. (2022) Assessment of Overweight, Obesity, Central Obesity, and Type 2 Diabetes among Adolescents in Qatar: A Cross-Sectional Study. Int J Environ Res Public Health., 19:14601.

Chun, S., Gopal, J., Muthu, M. (2021) Antioxidant Activity of Mushroom Extracts/Polysaccharides-Their Antiviral Properties and Plausible Anti COVID-19 Properties. Antioxidants (Basel)., 10:1899.

Wei, Q., Zhong, X., Meng, F., et al. (2021) Effect of Agaricus Blazei Murrill Extracts on Gut Microbiota in Diabetic Rats and Its Hypoglycemic Activity. Journal of China Food Science, 6:131-137.

Jeong, S., Jeong, Y., Yang, B., et al. (2010). White Button Mushroom (Agaricus Bisporus) Lowers Blood Glucose and Cholesterol Levels in Diabetic and Hypercholesterolemic Rats. Nutrition Research, 30:49–56.

Niwa, A., Tajiri, T., Higashino, H. (2011) Ipomoea Batatas and Agarics Blazei Ameliorate Diabetic Disorders with Therapeutic Antioxidant Potential in Streptozotocin-induced Diabetic Rats. J Clin Biochem Nutr., 48:194-202.

Mascaro, M.B., Franca, C.M., Esquerdo, K.F., et al. (2014) Effects of Dietary Supplementation with Agaricus Sylvaticus Schaeffer on Glycemia and Cholesterol after Streptozotocin-induced Diabetes in Rats. Evidence-Based Complementary and Alternative Medicine, 1-10.

Downloads

Published

22-11-2023

Issue

Section

Articles

How to Cite

Wei, Z. (2023). Research Progress of Agaricus blazei Polysaccharide on Blood Sugar in Diabetic Patients. International Journal of Biology and Life Sciences, 4(1), 37-40. https://doi.org/10.54097/ijbls.v4i1.11