Ji Desheng Snake Medicine for Herpes Zoster

Abstract

Objective: to evaluate the clinical efficacy and application value of Ji Desheng snake medicine in the treatment of herpes zoster by Meta-analysis. Methods: CNKI, WANFANG, VIP, PubMed, The Cochrane Library and Embase were searched to identify available articles (up to January 2024). The included articles were subjected to data extraction and bias risk evaluation, and ＲevMan5.3 software was used to evaluate the efficacy and safe recovery time. Results: Nine articles involving 459 patients were finally included. Meta-analysis showed that Ji Desheng snake medicine combined with conventional treatment could improve and shorten the disease recovery time of patients [MD = − 3.30, 95%CI (-5.50, -1.1%), P < 0.05]. Ji Desheng snake medicine combined with routine treatment tended to improve the curative effect, and the difference was not statistically significant [RR = 1.11, 95%CI (0.99, 1.24), P = 0.12]. Conclusion: Ji Desheng snake medicine combined with conventional antiviral therapy can shorten the course of herpes zoster, suggesting that the combination of Ji Desheng snake medicine and conventional antiviral drugs should be considered in the clinical treatment of herpes zoster. However, due to the large differences in the included literature, we should treat the research results carefully, and large sample size and high-quality literature are needed to further confirm its clinical efficacy.