Research on the Link Between Obesity and Cardiovascular Disease Risk
DOI:
https://doi.org/10.54097/m2jc0g35Keywords:
Obesity; cardiovascular disease; ordinal logistic regression.Abstract
This research examines the complex relationship between obesity and the risk of cardiovascular disease (CVD). Using a comprehensive dataset, we conducted a one-sample t-test to determine the significance of 17 variables related to obesity. The results showed that all variables, including demographic, lifestyle, and behavioral factors, significantly deviated from zero, indicating their importance in obesity studies. An ordinal logistic regression analysis was conducted to explore the predictors of obesity classification. The analysis revealed complex interactions among various factors. The study highlights the multifactorial nature of obesity and its impact on cardiovascular disease (CVD), providing insights for healthcare policies and future research directions. It particularly emphasizes the need to understand the role of less significant factors and the influence of cultural, environmental, and socioeconomic contexts on obesity. The implications of this research are significant for both the medical field and public health policy. The findings emphasize the intricate interplay of multiple factors in obesity and its correlation with the risk of cardiovascular disease. This comprehension could lead to more effective and targeted interventions, preventive measures, and policy formulations. For future research, it opens avenues to explore the role of less significant factors and to understand the impact of cultural, environmental, and socio-economic contexts on obesity. This study highlights the necessity of a comprehensive strategy to tackle the worldwide issue of obesity and its related health hazards.
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References
Loos R J F. Genetic determinants of common obesity and their value in prediction. Best practice & research Clinical endocrinology & metabolism, 2012, 26(2): 211-226.
Afshin A, Reitsma M B, Murray C J L. Health effects of overweight and obesity in 195 countries. The New England journal of medicine, 2017, 377(15): 1496-1497.
NCD Risk Factor Collaboration. Trends in adult body-mass index in 200 countries from 1975 to 2014: a pooled analysis of 1698 population-based measurement studies with 19.2 million participants. The lancet, 2016, 387(10026): 1377-1396.
Berenson G S, Srinivasan S R, Bao W, et al. Association between multiple cardiovascular risk factors and atherosclerosis in children and young adults. New England journal of medicine, 1998, 338(23): 1650-1656.
Powell-Wiley T M, Poirier P, Burke L E, et al. Obesity and cardiovascular disease: a scientific statement from the American Heart Association. Circulation, 2021, 143(21): 984-1010.
Mathew B, Francis L, Kayalar A, et al. Obesity: effects on cardiovascular disease and its diagnosis. The Journal of the American Board of Family Medicine, 2008, 21(6): 562-568.
Koliaki C, Liatis S, Kokkinos A. Obesity and cardiovascular disease: revisiting an old relationship. Metabolism, 2019, 92: 98-107.
Jensen M D, Ryan D H, Apovian C M, et al. Reprint: 2013 AHA/ACC/TOS guideline for the management of overweight and obesity in adults. J Am Pharm Assoc, 2014, 54(1): 3.
Iaccarino G, Ciccarelli M, Sorriento D, et al. Ischemic neoangiogenesis enhanced by β2-adrenergic receptor overexpression: a novel role for the endothelial adrenergic system. Circulation research, 2005, 97(11): 1182-1189.
Gordon-Larsen P, Heymsfield S B. Obesity as a disease, not a behavior. Circulation, 2018, 137(15): 1543-1545.
Poirier P, Giles T D, Bray G A, et al. Obesity and cardiovascular disease: pathophysiology, evaluation, and effect of weight loss: an update of the 1997 American Heart Association Scientific Statement on Obesity and Heart Disease from the Obesity Committee of the Council on Nutrition, Physical Activity, and Metabolism. Circulation, 2006, 113(6): 898-918.
Britton K A, Massaro J M, Murabito J M, et al. Body fat distribution, incident cardiovascular disease, cancer, and all-cause mortality. Journal of the American College of Cardiology, 2013, 62(10): 921-925.
Piché M E, Poirier P, Lemieux I, et al. Overview of epidemiology and contribution of obesity and body fat distribution to cardiovascular disease: an update. Progress in cardiovascular diseases, 2018, 61(2): 103-113.
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