Application and Development Prospect of Metagenomes in the Identification of Intestinal Microorganisms

Abstract

Intestinal microorganisms are the result of long -term coexistence coordination of microorganisms and hosts in the human body, which plays an important role in maintaining normal physiological functions and regulating human health. With the development of metagenomic sequencing technology, the research on gut microbes has become more in-depth. Researchers have used metagenomic technology to identify the composition of the intestinal flora in patients with diseases and compare it with the composition of the intestinal flora in healthy people to study the pathogenesis of related diseases. At present, there is still a lack of unified standard process for metagenomic technology, and the study of the internal mechanism of intestinal flora affecting diseases has not been in-depth. Future research can integrate multi-omics methods to conduct in-depth research on the dynamic changes of intestinal flora. This paper reviews the current research progress of intestinal flora and mental diseases, metabolic diseases of obesity and cancer after applying metagenomic technology to intestinal microbes, hoping to better identify the important role of intestinal microbes in the study of disease occurrence, treatment and prevention, and provide a reference for related studies.