Emerging Insights into the Principles and Advantages of Single-Cell and Spatial Transcriptomics

Boyu Zhu

doi:10.54097/gf62sx56

Authors

Boyu Zhu

DOI:

https://doi.org/10.54097/gf62sx56

Keywords:

Single-cell transcriptome sequencing; High-throughput analysis; Spatial transcriptome sequencing; Spatial location information; Cell transcriptome.

Abstract

Single-cell transcriptomics is a high-throughput technology capable of analyzing gene expression at the individual cell level. Spatial transcriptomics, on the other hand, is a technique that simultaneously captures both gene expression profiles and the spatial location information of cells. While single-cell transcriptomics enables sequencing of the transcriptome at a single-cell resolution, spatial transcriptomics provides the added dimension of spatial context alongside gene expression data. These two approaches—single-cell transcriptomics and spatial transcriptomics—are complementary, and their integration can facilitate a more comprehensive and in-depth investigation of biological questions.

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