The Relationship of Sleep Duration, Chronotype and the Risk of Depression: A Systematic Review and Meta-analysis
DOI:
https://doi.org/10.54097/69ymgj60Keywords:
Sleep Duration, Chronotype, Depression, Meta-AnalysisAbstract
Depression is one of the greatest health challenges worldwide, and sleep is a major influencing factor in depression. This meta-analysis aimed to systematically integrate existing evidence by analyzing 34 observational studies from five electronic databases. Results revealed that short sleep duration (OR=1.78, 95% CI: 1.61–1.97), long sleep duration (OR=1.17, 95% CI: 1.02–1.34), neutral chronotype (N-type) (OR=1.27, 95% CI: 1.06–1.51), and evening chronotype (OR=2.09, 95% CI: 1.64–2.68) were associated with an increased risk of depression. Specifically, short sleep duration and evening chronotype were more significantly associated with the risk of depression. This meta-analysis demonstrated that both short and long sleep durations, and evening chronotype are associated with an elevated risk of depression. Due to substantial heterogeneity among studies, the evidence base remains limited. Future research should employ standardized methods, longitudinal designs, and investigate contextual factors to clarify underlying mechanisms.
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