The pathogenesis and drug treatment of aortic dissection

Abstract

Aortic coarctation belongs to a life-threatening condition in which the walls of the true and false aorta separate. There are two classifications: type A and type B. Current treatments include surgery and taking medications. This research analyzes the results of previous literature on drugs for aortic coarctation treatment to summaries effective drug treatments from previous studies. The main topics in the article include pharmacological induction of endothelial dysfunction in mice and studying the therapeutic effects of pitavastatin for aortic coarctation, comparing the possible associations between antihypertensive medications, antithrombotic drugs, anticoagulant medications, and statins, and long-term survival. In addition, this research focuses on the therapeutic effects of statins, antihypertensive drugs, antithrombotic drugs, and anticoagulant drugs in aortic coarctation and their association with long-term survival, to provide a cross-sectional comparison of drugs and the advantages and disadvantages of different modes of nonsurgical treatment for aortic coarctation. The advantages and disadvantages of different therapeutic modalities.