Traditional and Novel Treatments for Systemic Lupus Erythematosus
DOI:
https://doi.org/10.54097/x4hq2v29Keywords:
Systemic Lupus Erythematosus; Autoimmune disease; Lupus Nephritis; Belimumab (BLM); Stem Cell Therapy.Abstract
Being one of the most complicated autoimmune diseases in the world, Systemic Lupus Erythematosus (SLE) has been researched for years, yet the underlying mechanism remains unclear. This literature review aims to provide a brief overview of SLE symptoms and complicated diseases, namely the formation of malar rash, arthritis, and multiorgan failure. Additionally, the pathogenesis of SLE will be discussed, analyzing the relationship between apoptotic clearance, adaptive immunity and SLE. Followed by an examination of various treatment methods. The effectiveness and safety of these treatments will also be evaluated. Furthermore, this review will explore the possibility of Stem Cell Therapy as a novel treatment for SLE. Cases of using stem cell therapy as a treatment for SLE will be studied and analyzed to determine its feasibility and potential risks. By critically reviewing published papers and recent studies, this literature review seeks to offer an introduction to the symptoms of the disease, assess the safety, effectiveness, and side effects of the current mainstream treatments, and propose stem cell Therapy as an innovative treatment to SLE.
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