Classification of drugs for the treatment of circadian rhythm disorders
DOI:
https://doi.org/10.54097/hset.v54i.9753Keywords:
circadian disorder, drug therapy, classification.Abstract
Survey studies found that more than 3% of adults have CRSD, and about 16% of teenagers may have CRSD. Although it may be self-limiting, others will cause burden consequences. Many existing papers on drug classification focus on the classification method, or discuss some drug characteristics, but because the target range of drugs is too large, there is no way to expand each drug mentioned, and make their characteristics more detailed and clear. With the development of sleep drug research, there are a lot of reviews on the regulation of circadian rhythm, especially on the circadian rhythm disturbance, but most of them are very detailed studies on a specific drug, such as melatonin or amphetamine. The drugs used to treat circadian disorders can be classed as sedative hypnotics, stimulant stimulants, chronotropic drugs, and gives a cursory mention of other drugs that do not fall into the first three categories. Among the sedatives and hypnotics, barbiturates, benzodiazepines and other drugs include tranquilizers or non-benzodiazepines. Amphetamine, Modafinil and caffeine were mentioned in the stimulant category. The third category of drugs that is mainly described is melatonin. This paper is based on the classification of drugs that regulate circadian rhythm disorders. For each category, at least several representative drugs are proposed and their characteristics are described. It contains basic information about the drug, its properties, mechanism of action, side effects and so on. In the description of drug characteristics, there are also some parts of this article that compare drug effects horizontally. The section on stimulant function discusses how long three different drugs can help to maintain a state of arousal, Differences in side effects were also compared.
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References
Kim, M. J., Lee, J. H., & Duffy, J. F. (2013). Circadian Rhythm Sleep Disorders. Journal of clinical outcomes management: JCOM, 20(11), 513–528.
Zheng Junwei, Meng Shiqiu, Liu Yueming, et al. Rational use and abuse of sedative-hypnotic drugs [J]. Journal of Sichuan University (Medical Science Edition), 2023, 54(2): 231-239.
Thorpy, M. J., & Roth, T. (2013). Toward a classification of medications for sleep and circadian rhythm disorders. Nature and science of sleep, 5, 143–145.
Neubauer, D. N., Pandi-Perumal, S. R., Spence, D. W., Bottoo, K.,& Monti, J. M.(2018). Pharmacotherapy of Insomnia. Journal of Central Nervous System DiseaseZ: JOUR
Deng Yuhong. Rational selection of hypnotic sedatives and pharmaceutical research [J]. China Medical Herald, 2010,7(2):44-45.
Martin, D., & Le, J. K. (2022). Amphetamine. In StatPearls. StatPearls Publishing.
David J Heal, Sharon L Smith, and David J Nutt, Amphetamine, past and present – a pharmacological and clinical perspective)
Greenblatt, K., & Adams, N. (2023). Modafinil. In StatPearls. StatPearls Publishing.
Evans, J., Richards, J. R., & Battisti, A. S. (2022). Caffeine. In StatPearls. StatPearls Publishing.
Kim D. (2012). Practical use and risk of modafinil, a novel waking drug. Environmental health and toxicology, 27, e2012007.
Arendt, J., & Aulinas, A. (2022). Physiology of the Pineal Gland and Melatonin. In K. R. Feingold (Eds.) et. al., Endotext. MDText.com, Inc.
Awosika, A., J. Adeniyi, M., K. Okojie, A., & Okeke, C. (2023). Photic Stress and Rhythmic Physiological Processes: Roles of Selenium as a Chronobiotic. Selenium and Human Health [Working Title].
Savage, R. A., Zafar, N., Yohannan, S., & Miller, J. M. M. (2022). Melatonin. In StatPearls. StatPearls Publishing.
Dominguez, A., Soca Gallego, L., & Parmar, M. (2023). Sodium Oxybate. In StatPearls. StatPearls Publishing.
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