Exploring the anti-inflammatory effects of spinach sterols based on network pharmacology
DOI:
https://doi.org/10.54097/hset.v8i.1307Keywords:
Cyber pharmacology; Spinach sterols; Anti-inflammatory; Molecular docking.Abstract
Aims To investigate the anti-inflammatory mechanism of action of spinach sterol (Spinasterol) by network pharmacology and molecular docking. METHODS: Firstly, the TCMSP database was used to find the targets of action of spinasterol, and then the pubchem database and UniProt database were used to analyze and predict the mechanism of action of the targets in spinasterol. Conclusion: Spinach sterols achieve anti-inflammatory effects through three mechanisms of action: modulation of immune molecular mediators, activation of immune cells and direct action on inflammatory cells.
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