Application of Nanotechnology in Organ Transplantation

Abstract

Organ transplantation can serve as a blessing for end-stage organ patients, and issues such as organ shortage and transplantation risks also make research on organ transplantation very important. Nanotechnology involves the development of materials called nanoparticles, which are defined as having a one-dimensional range of at least 1 to 100 nm. This paper introduces the application of nanotechnology in overcoming the drawbacks of traditional medicine, and its nanoscale size has also contributed to organ transplantation. The combination of Magnetic resonance imaging (MRI) and Magnetic hyperthermia (MHT), nanoparticles can better capture transplant medical images, and nanotechnology plays an important role in monitoring treatment responses and designing organ transplantation methods. CRISPR/CAS9 system and Entrancer™ can reduce the role in rejection reactions. Normothermic Machine Perfusion (NMP), protein corona, and curcumin can reduce their effects on ischemia-reperfusion injury. The development of nanomedicine can provide a platform for significant progress in transplant vitality. In future research, nanoparticles can also be applied in 3D bioprinting and artificial intelligence (AI) to better assist in transplant therapy.