Pharmacological Effects and Related Mechanisms of Ganoderma Lucidum Polysaccharides at the Cellular Level

Ziheng Zhang; Peiyao Song; Yueqi Zhao; Yuhang Li; Kuangzhen Shao; Guangjie Bao; Manli Guo

doi:10.54097/vd1ry878

Authors

Ziheng Zhang
Peiyao Song
Yueqi Zhao
Yuhang Li
Kuangzhen Shao
Guangjie Bao
Manli Guo

DOI:

https://doi.org/10.54097/vd1ry878

Keywords:

Ganoderma lucida; Ganoderma lucidum polysaccharide; Pharmacological effect; Anti-tumor; anti-oxidation; anti-aging; hypoglycemic; immune regulation.

Abstract

Ganoderma lucidum polysaccharides are the primary active constituents of Ganoderma lucidum. Existing researches indicate that they possess multiple pharmacological effects and benefits, including anti-tumor, antioxidant, anti-aging, hypoglycemic, and immune-modulating properties. Studies on the cellular impact of Ganoderma polysaccharides have predominantly focused on various cell types, including malignant tumor cells, immune cells, cardiac myocytes, neurons, hepatocytes, and fibroblasts. In this paper, we review and summarize recent literature primarily related to these pharmacological effects at the cellular level and their underlying mechanisms. Our aim is to provide insights and references for the deep clinical development and utilization of Ganoderma lucidum polysaccharides.

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