Vaccination therapy of Canine Parvovirus (CPV) infected on dogs

Abstract

Canine Parvovirus (CPV) is highly contagious virus, it has become the most remarkable factor for causing death among pet dogs since it was discovered and recorded in the decades. The variant CPV-2 attacks rapid dividing cells after entering blood flow, leading to inflammation in heart, for puppies, and small intestines, for adults, both of the disorders are extremely fatal. Currently, there are no effective treatments to fully treat myocarditis and enteritis caused by CPV-2, the best way to resist the diseases for patients to receive conservative treatment, including analgesia, antiemesis, antidiarrhea, intravenous nutrition. New therapies like Ozone therapy and fecal microbiota transplantation (FMT), have a good therapeutic effect, reduce mortality to some extent, which are quite prospecting. As a result, the best choice is to take prevention by injecting vaccines. Contemporary vaccines can be divided into attenuated vaccines and inactivated vaccines, which are relatively easy to be synthesised and are used in a wide range, and virus-like particles (VLP), all of them can produce antibodies against CPV-2.